A widespread problem in both fruit and horticulture is the increasing difficulty in obtaining qualitatively and quantitatively satisfactory yields due to a number of factors attributable to ‘soil fatigue’. Ryzoclean is a product based on microelements complexed with plant extracts containing tannins and inactivated Saccharomyces cerevisiae yeast extracts, designed to regenerate the fertility of tired and depleted soils and to promote plant development, even under adverse conditions. Ryzoclean applications have a positive effect on the chemical and physical properties of the soil, facilitating the growth of both field and greenhouse crops. Finally, thanks to its acidic pH, the product creates a favourable environment for nutrient uptake.